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1522_C02.fm  Page 72  Wednesday, November 12, 2003  9:36 AM













                                                3.0
                                                2.0                                         TIC
                                                1.0
                                                0.0
                                                           1      2       3       4      5
                                                0.5
                                                                                        Morphine
                                                                                         m/z: 286
                                                0.0
                                                           1      2       3      4       5
                                                0.5                                      Codeine
                                                                                         m/z: 300
                                                0.0
                                                           1      2       3      4       5
                                                0.5                                      6-MAM
                                                                                         m/z: 328
                                                0.0
                                                           1      2       3      4       5
                                                2.0
                                                                                       Papaverine
                                                1.0                                      m/z: 340
                                               Intensity (×10 6 )  0.4  1  2  3  4       5 Heroin
                                                0.0


                                                0.2
                                                0.0                                      m/z: 370
                                                           1      2       3      4       5
                                                0.4                                  Acetylcodeine
                                                                                         m/z: 342
                                                0.2
                                                0.0
                                                           1      2       3      4       5
                                                                                       Noscapine
                                                0.5
                                                                                         m/z: 413
                                                0.0
                                                           1      2       3      4       5
                                                1.0
                                                                                            JS
                                                0.5                                      m/z: 284
                                                0.0
                                                           1      2       3      4       5
                                                                     Time (min)
                                    Figure 2.2  Total ion and selected ion chromatograms of a mixture (1 mg/l) of
                                    the opium alkaloids and the internal standard. (Reprinted with permission from
                                    Anal. Chem. 74, 3206, 2002. Copyright 2002 American Chemical Society.)





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