Page 86 - Advances in Forensic Applications of Mass Spectrometry - Jehuda Yinon

1522_C02.fm Page 74 Wednesday, November 12, 2003 9:36 AM
42
43
44
0.25–0.5
1.0–5.0
0.5–5.0
ESI-QQQ, MRM
ESI-QQQ, MRM
ESI-Q, SIM
C18, ACN-HCOONH 4 isocr.
C18, ACN-HCOONH 4 grad.
C18, ACN-HCOOH isocr.
Isolation m m Ref. LOD (mg/l) m Detection Column, Elution Conditions Sample 20 0.5–1.0 ESI-QQQ, MRM Silica, ACN-HCOOH isocr. SPE 21 0.5–10 ESI-QQQ, MRM Silica, ACN-TFA isocr. SPE 96 40 10.0 ESI-Q, SIM C8, ACN-HCOONH 4 isocr. L/l Plasma, urine 41 0.3–2.5 ESI-QQQ, MRM C18, ACN-HCOOH grad. SPE 39 0.
SPE
SPE
SPE
LC/MS Methods Used for Opioids Plasma Plasma Serum, urine Serum, urine Serum Serum Plasma Plasma Plasma Plasma (rat) Plasma Urine

Table 2.1 Drug M, M3G, M6G M, M3G, M6G M, 6-MAM, Cod, NorCod, Pholcod M, M3G, M6G, NorM M, M3G, M6G, 6-MAM, Cod, C6G M, M3G, M6G, 6-MAM, Cod, C6G M, M3G, M6G M, M3G, M6G Fentanyl HYM, HYC HYM, DHM, H3G, other metabolites Buprenorphine, BUG, NBUG Ketobemidone, Nor-K Notes: © 2004 by CRC Press LLC