Page 98 - Advances in Forensic Applications of Mass Spectrometry - Jehuda Yinon
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1522_C02.fm  Page 84  Wednesday, November 12, 2003  9:36 AM

                                   Ref.  72  73  32  80  87  90  92

                                   LOD (mg/l)  1–5  0.4–0.8  1.0  1.0  0.5–2.0  2.8–4.4  25 pg/mg
                                   m  m  m





                                   Detection  APCI-Q, SIM  ESI-Q, SIM  ESI-qTOF/SIM  ESI-QQQ, MRM  ESI-QQQ, MRM  ESI-QQQ, MRM  ESI-QQQ, MRM







                                   Column, Elution Conditions  C18, ACN-HCOONH 4  isocr. CN, ACN-CH 3 COONH 4  isocr. C18, ACN-CH 3 COONH 4  isocr. C18, ACN-CH 3 COONH 4  isocr. C18, ACN-H 2 O gradient C8, MeOH/ACN-CH 3 COONH 4  isocr. C18, ACN-CH 3 COONH 4  gradient A = amphetamine, MA = methamphetamine, MDMA = methylenedioxymethamphetamine,










                                LC/MS Methods Used for Amphetamines and Cocaine



                                   Isolation  SPE  SPME  l/l  SPE  SPE  SPE  SPE quadrupole, qTOF = quadrupole/time-of-flight, SIM = selected ion monitoring, MRM = multiple reaction monitoring, ACN = acetonitrile.




                                   Sample  Plasma  Urine  Plasma  Saliva  Urine  Plasma  Hair











                                   Drug 14 Amphetamines and related compounds A, MA, MDMA, MDEA, MDA  A, MA, MDMA, MDEA, MDA, E  Cocaine, BZE, cocaethylene  © 2004 by CRC Press LLC




                                Table 2.2  MDMA, MDEA, MDA  Cocaine, BZE, EME Cocaine, BZE, EME, ECG  Notes:
   93   94   95   96   97   98   99   100   101   102   103