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1522_C02.fm  Page 89  Wednesday, November 12, 2003  9:36 AM











                                               6000.00                                     A
                                               5000.00

                                               4000.00
                                                                                          [−20°C]
                                               pg/mL  3000.00                           X  [0°C]
                                                                                          [24°CL]
                                                                                          [24°CN]
                                                                                          [50°C]
                                               2000.00
                                               1000.00

                                                 0.00
                                                     0  1  2   3  4  5   6  7   8  9  10
                                                                    Days
                                               6000.00                                     B

                                               5000.00
                                                                                   X
                                               4000.00
                                                                                          [−20°C]
                                               pg/mL  3000.00                           X  [0°C]
                                                                                          [24°CL]
                                                                                          [24°CN]
                                                                                          [50°C]
                                               2000.00
                                               1000.00
                                                 0.00
                                                     0  1  2   3  4  5   6  7   8  9  10
                                                                    Days
                                               6000.00                                     C
                                               5000.00

                                               4000.00
                                                            X                             [−20°C]
                                               pg/mL  3000.00      X                    X  [0°C]
                                                                                          [24°CL]
                                                                                          [24°CN]
                                                                                          [50°C]
                                                                                    X
                                               2000.00
                                               1000.00
                                                 0.00
                                                     0  1  2   3  4  5   6  7   8  9  10
                                                                    Days
                                    Figure 2.8  Stability of 2-oxo-3-hydroxy-LSD at pH 4.6 (A), 6.5 (B), and 8.4 (C)
                                    at different storage conditions. (From Klette K.L., Horn C.K.,  Stout P.R., and
                                    Anderson C.J., LC-MS analysis of human urine specimens for 2-oxo-3-hydroxy
                                    LSD: Method validation for potential interferants and stability study for 2-oxo-
                                    3-hydroxy LSD under various storage conditions. J. Anal. Toxicol. 26, 193, 2002.
                                    Reproduced from the Journal of Analytical Toxicology by permission of Preston
                                    Publications, a division of Preston Industries, Inc.)



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