Page 105 - Advances in Forensic Applications of Mass Spectrometry - Jehuda Yinon

1522_C02.fm Page 90 Wednesday, November 12, 2003 9:36 AM

Ref. 97 98 100 101 105 107 110 111 112

LOD (mg/l) 1.0 0.25 0.5 10.0 0.5 0.2 0.4 0.1–0.4
m m m 0.025

Detection APCI-QIT, SIM APCI-QQQ, MRM ESI-Q, SIM ESI-QQQ ESI-Q, SIM ESI-QQQ, MRM APCI-QIT, SIM APCI-QIT, SIM ESI-Q, SIM

Column, Elution Conditions C8, MeOH-HCOONH 4 isocr. C8, MeOH-HCOONH 4 isocr. C18, MeOH-CH 3 COONH 4 isocr. C8, ACN-HCOONH 4 grad. C18, ACN-CH 3 COONH 4 isocr. Phenyl, ACN-CH 3 COONH 4 C18, ACN-CH 3 COONH 4 isocr. C18, ACN-CH 3 COONH 4 grad. C18, MeOH-HCOONH 4 grad. Notes: THC = tetrahydrocannabinol, T

LC/MS Methods Used for Cannabinoids and Hallucinogens

Isolation SPE SPE SPE L/l SPE SPE L/l+SPE L/l+SPE L/l+SPE

Sample Plasma, urine Plasma, urine Urine Urine Urine Blood, urine Urine Urine Blood, urine

Drug THC, OH-THC, THCCOOH THC, OH-THC, THCCOOH THCCOOH, THCCOOH-G © 2004 by CRC Press LLC

Table 2.3 THCCOOH LSD, Nor-LSD LSD, Nor-LSD LSD, O-H-LSD LSD, O-H-LSD LSD, O-H-LSD