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Exercises  169


               freshmen in a programming course (Porto University), based on the Program ming
               dataset.
               Use the Levene test to check the equality of variance assumption and determine the
               power of the test.

           4.24 Perform the following post-hoc comparisons for the previous exercise:
               a)  Scheffé test.
               b)   “No previous knowledge” vs. “Some previous knowledge” contrast. Compare the
                   results with those obtained in Exercise 4.19

           4.25 Consider the comparison of the bacterial counts as described in the CFU   datasheet of
               the Cells   dataset (see Exercise 4.9) for the spleen and the liver at two weeks and at
               one and two months (“time of count” categories). Using two-way ANOVA performed
               on the first 5 counts of each group (“knock-out” and “control”), check the following
               results:
               a)  In what concerns the spleen, there are no significant differences at 5% level either
                   for the group categories or for the “time of count” categories. There is also no
                   interaction between both factors.
               b)  For the liver there are significant differences at 5% level, both for the group
                   categories  and  for the “time of count” categories.  There is also a significant
                   interaction between these factors as can  also be inferred from the respective
                   marginal mean plot.
               c)  The test power in this last case is above 80% for the main effects.

           4.26 The SPLEEN   datasheet of the C ells   dataset contains percent counts of bacterial load
               in the spleen of two groups of  mice (“knock-out”  and “control”) measured by two
               biochemical markers (CD4 and CD8). Using two-way ANOVA, check the following
               results:
               a)  Percent  counts after  two weeks of bacterial infection exhibit significant
                   differences at  5% level for the group  categories, the biochemical marker
                   categories and the interaction of these factors. However, these results are not
                   reliable since the observed significance of the Levene test is low (p = 0.014).
               b)  Percent  counts after two months of bacterial infection exhibit a significant
                   difference (p = 0) only for the biochemical marker. This is a reliable result since
                   the observed significance of the Levene test is larger than 5% (p = 0.092).
               c)  The power in this last case is very large (p ≈ 1).

           4.27 Using  appropriate contrasts check  the following results  for the ANOVA study of
               Exercise 4.24 b:
               a)  The difference of means for the group categories is significant with p = 0.006.
               b)  The difference of means for “two weeks” vs “one or two months” is significant
                   with p = 0.001.
               c)  The difference of means of the time categories for the “knock-out” group alone is
                   significant with p  = 0.027.
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