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Chapter 6 Additional clinical applications 193




                     results of CFD computations. Fig. 6.5 displays the workflow for
                     mesh pre-processing.
                        The synthetic vessel model consists of two separately param-
                     eterized functions: one for describing the vessel centerline, and
                     one for describing the surface. The vessel centerline is a three-
                     dimensional Bezier curve defined by five control points, while the
                     surface model is a function ¯ =¯r(z,φ),where r is the vessel radius,
                                              r
                     z is the position on the centerline, and φ is the angle. The surface
                     points are expressed in cylindrical coordinates with respect to the
                     vessel centerline, as displayed in Fig. 6.6
                        The Cartesian (x,y,z) to cylindrical coordinates (z,r,φ) trans-
                     formation allowed us to express the radius, the most relevant char-
                     acteristic for the CoA segment, as an explicit function of two vari-
                     ables (z and φ), i.e. represent it as a three-dimensional explicit
                     surface. The main goal of this step is to fit a function ¯ =¯r(z,φ)
                                                                       r
                     to the given points, to obtain a parameterized encoding of the sur-
                     face. The transformation from Cartesian to cylindrical coordinates
                     is performed in two steps:
















                     Figure 6.5. Workflow for pre-processing the patient-specific anatomical models.




















                     Figure 6.6. Transforming 3D surface points to cylindrical coordinates, with respect to the centerline position.
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