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CHAPTER
Laser-assisted cancer
treatment 6
Chapter outline
6.1 Predicting the optical properties ........................................................................ 131
6.1.1 Mie theory .....................................................................................132
6.1.2 Discrete dipole approximation .........................................................133
6.2 Photothermal therapy ........................................................................................ 134
6.2.1 Gold nanoshells .............................................................................134
6.2.2 Gold nanorods ...............................................................................135
6.2.3 Gold nanocage ...............................................................................138
6.2.4 Gold nanostars...............................................................................138
6.2.5 Carbon nanotubes ..........................................................................138
6.2.6 Graphene ......................................................................................139
6.3 Photodynamic therapy ....................................................................................... 141
6.3.1 Methylene blue ..............................................................................142
6.3.2 Photogem......................................................................................142
6.3.3 Chlorins ........................................................................................142
6.3.4 Curcumin ......................................................................................143
6.3.5 Phthalocyanines ............................................................................143
6.3.6 Hypericin ......................................................................................143
6.4 NIR-triggered anticancer drug delivery ............................................................... 145
6.4.1 Photothermal-guided drug release (PT-NIRSRS) ................................145
6.4.2 Two-photon conversion guided drug release (TP-NIRSRS) ..................148
6.4.2 Upconverting nanoparticles guided drug release (UP-NIRSRS) ...........148
6.5 Cross-section absorption of graphene oxide ....................................................... 149
6.5.1 Minimization of lateral thermal diffusion and scattering .....................149
6.5.2 Obtaining cross-section absorption of GO .........................................149
References .............................................................................................................. 152
6.1 Predicting the optical properties
There are several models to numerically predict the optical properties of various
geometries such as Mie theory, boundary element, discrete dipole approximation,
and finite element method. Mie theory and discrete dipole approximation will be
discussed in the following.
Bio-Engineering Approaches to Cancer Diagnosis and Treatment. http://dx.doi.org/10.1016/B978-0-12-817809-6.00006-6 131
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