Page 114 - Biobehavioral Resilence to Stress
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Adaptation to Stress
and Psychobiological 5
Mechanisms of
Resilience
STEVEN M. SOUTHWICK
Yale University School of Medicine
National Center for PTSD
FATIH OZBAY
Yale University School of Medicine
DENNIS CHARNEY
Mount Sinai School of Medicine
BRUCE S. McEWEN
The Rockefeller University
Contents
The Stress Response ............................................................................................. 92
Adaptation to Stress ........................................................................................ 93
Stress and the Brain ............................................................................................. 95
Neurochemistry of Resilience to Stress............................................................. 97
Autonomic Nervous System Responses to Stress ....................................... 97
Hypothalamic-Pituitary-Adrenal Axis Responses to Stress ..................... 99
Genetic Factors Associated with SNS and HPA Responses to Stress ......... 100
Developmental Influences on SNS, HPA, and Resilience ............................. 102
Psychosocial Factors of Allostatic Load and Resilience ............................... 103
Dispositional Optimism ............................................................................... 103
Exercise ........................................................................................................... 105
Social Support ................................................................................................ 106
Possible Interventions ................................................................................... 107
References ............................................................................................................ 108
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