Page 198 - Biomedical Engineering and Design Handbook Volume 2, Applications

DESIGN OF CONTROLLED-RELEASE DRUG DELIVERY SYSTEMS 177

TABLE 6.2 Examples of Various Marketed Controlled-Release Drug Delivery Products (Continued)
Product Route of Developer/
Design Principle Name Active Ingredient Administration Manufacturer
Biodegradable/ Cipro XR Ciprofloxacin Oral tablet Schering Plough
erodable matrix Paxil CR Paroxetine Oral tablet Glaxo Smith Kline
Ambien CR Zolpidem tartarate Oral tablet Sanofi Aventis
Risperidal Consta Risperidone Parenteral J&J (Ortho McNeil)
Locteron rAlpha interferon Parenteral Biolex
Sinemet CR Carbidopa Tablet Merck
and levedopa
hGH-OctoDEX hGrowth hormone Parenteral Octoplus
Naprelan Naproxen sodium Tablet Roche
Abraxane Paclitaxel Parenteral Abraxis/Astrazeneca
Gliadel Wafer Carmustine Implant MGI Pharma
Zoladex Goserelin Implant Astrazeneca
Remoxy Oxycodone Capsule Durect
Gastroretentive Valrelease Levedopa Oral capsule Roche
dosage Topalkan Al-Mg antacid Tablet Pierre Fabre Sante
with alginic acid
Gaviscon Alginates Tablet Glaxo Smith Kline
Glumetza Metformin Tablet Depomed/King
Pharma
Proquin XR Ciprofloxacin Tablet Depomed
Gabapentin GR Depomed Tablet Depomed

Osmotic pumps Calan SR Verapamil Oral tablet Alza/GD Searle
Cardura XL Doxazosin Oral tablet Alza/Pfizer
Covera HS Verapamil Oral tablet Alza/ Pfizer
DUROS Potential carrier for Implant Alza
macromolecules
Ditropan Oxybutynin Oral tablet Alza/UCB Pharma
Minipress XL Prazosin Oral tablet Alza/Pfizer
Teczem Enalapril Oral tablet Merck/Aventis
and diltiazem
Glucotrol XL Glipizide Oral tablet Pfizer
Concerta Methylphenidate Oral tablet J&J (Ortho McNeil)
Procardia XL Nifedipine Oral tablet Pfizer
Dyna Circ CR Isradipine Oral tablet Reliant Pharma
Sudafed 24h Pseudoephidrine Oral tablet Pfizer
Volmax Albuterol Oral tablet Alza/Muro
Pharmaceuticals
Liposome Ambisome Amphotericin B Parenteral Gilead/Astellas
Amphotec Amphotericin B Parenteral Sequus
Pharmaceuticals
Doxil Doxorubicin Parenteral Sequus
Pharmaceuticals
DaunoXome Daunorubicin Parenteral Diatos/Gilead
Liprostin PGE-1 Parenteral Endovasc
Depocyt Cytarabine Parenteral Skye Pharma
Abelcet AmphoterecinB Parenteral Enzon
LipoTaxen Paclitaxel Parenteral Lipoxen
(Continued)