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Bar-Cohen : Biomimetics: Biologically Inspired Technologies  DK3163_c007 Final Proof page 217 21.9.2005 11:41am




                    Bio-Nanorobotics                                                            217



                                           A      D           B            The SPHERE represents
                                                                           energy and data storage
                                                                           arrangements for the robat
                                           B      A     B
                       C
                                                  C





                                                                                 The RING represents the
                                              The DISC represents spatial       spatial area defined on the
                                               area defined for Module D         inner core for the binding
                                              and for possible connections        of the Module B and
                                                                                     Module C
                    Figure 7.12 (See color insert following page 302)  (A)Abio-nanoroboticentity‘‘ABCD’’,whereA,B,C,andDare
                    the various bio-modules constituting the bio-nanorobot. In our case these bio-modules will be set of stable configur-
                    ations of various proteins and DNAs. (B) A bio-nanorobot (representative), as a result of the concept of modular
                    organization. All the modules will be integrated in such a way so as to preserve the basic behavior (of self-assembly
                    and self-organization) of the biocomponents at all the hierarchies. The number of modules employed is not limited to
                    four or any number. It is a function of the various capabilities required for a particular mission. (C) A molecular
                    representation of the figure in part B. It shows the red core and green and blue sensory and actuation bio-modules.



                      (b) The Universal Template — BioNano STEM System: The modular construction concept
                    involves designing a universal template for bionanosystems, which could be ‘‘programmed and
                    grown’’ into any possible bionanocoded system. This concept mimics the embryonic stem cells
                    found in the human beings, that are a kind of primitive human cells which give rise to all other
                    specialized tissues found in a human foetus and ultimately to all the three trillion cells in an
                    adult human body. Our BioNano STEM system will act in a similar way. This universal growth
                    template will be constituted of some basic bionanocodes, which will define the BioNano
                    STEM system. This STEM system will be designed in a manner that could enable it to be
                    programmed at runtime to any other required bio-module. Figure 7.14 shows one such variant of




                                                    EIWR || M || S || FG





                          Module A             Module B           Module C            Module D





                         I   E    R              M                   S                 F   G
                             W
                                                                           Sub Modules

                    Figure 7.13  Showing the bio-nano code and the fractal modularity principle. The letter symbols have the values
                    specified in Table 7.1. The ‘‘k’’ symbol integrates the various bio-modules and collectively represents a higher order
                    module or a bio-nanorobot.
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