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34      2 Method Development and Optimization of Enantiomeric Separations Using …

                3b)




                                                                             tetrahydrofu-












                                                                               °C). 4.6 mm) with the same mobile phase composition:
                                                                               at ambient temperature (23








































                                                                             Fig. 2-3. The enantiomeric separation of profens on vancomycin CSP (250 × sodium citrate (10/90 v/v) pH 6.3. The flow rate was 1.0 mL min –1  20 mM  ran:
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