Page 60 - Chiral Separation Techniques
P. 60
36 2 Method Development and Optimization of Enantiomeric Separations Using …
4b)
Fig. 2-4. The enantiomeric separation of α-hydroxy/halogen acids on ristocetin A CSP (250 × 4.6 mm)
with the same mobile phase composition: methanol with 0.02 % acetic acid and 0.01 % triethylamine
–1
(v/v). The flow rate was 1.0 mL min at ambient temperature (23 °C).
