Page 166 - Color Atlas of Biochemistry

Carbohydrate Metabolism 157

A. Glycogen metabolism

α-1,4-Glucan chain α-1,4-Glucan chain
(unbranched) (α-1,6-branched)
3

R
R

Reducing
end
U
P
P P
4
UDP- 2 Degra- 4
glucose dation
U
P
P P
Glucose 1-
phosphate
P P 4
1 R
UTP Further
R
degradation
P
5
Glucose
1-phosphate
6
Building block
synthesis Glucose R

UTP-glucose 1-phosphate
1 4 Phosphorylase 2.4.1.1
uridyltransferase 2.7.7.9
2 Glycogen synthase 2.4.1.11 5 4-α-Glucanotransferase 2.4.1.25

3 Glucan branching enzyme 6 Amylo-1,6-glucosidase
2.4.1.18 3.2.1.33

B. Glycogen balance

Liver Liver Blood Muscle Muscle
glycogen 4 – 6 g · l -1 glycogen 300 g

Blood
Glucose glucose Glucose
1-phosphate 1-phosphate

150 g 200 g
De-
Glucose Glucose Degra-
6-phosphate grad- 6-phosphate dation
ation
1 g
Glucose Glucose Glucose

Liver Muscle
glycogen glycogen

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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