Page 168 - Color Atlas of Biochemistry

Carbohydrate Metabolism 159

A. Regulation of carbohydrate metabolism

Epinephrine Glycogen Epinephrine
Glucagon Glucagon

Insulin 1 2 AMP
Fru-2,6-bis P ATP
Insulin Glucose Insulin AMP Citrate
1-phosphate

3 5
3'
Glucose Fructose Fructose1,6-
Glucose
6-phosphate 6-phosphate bisphosphate

4 6
R
Insulin
R
Cortisol Insulin Cortisol Fru 2,6-bis P
Glucagon Glucagon AMP

Glucagon
ATP
Insulin Acetyl CoA 1 Glycogen synthase 2.4.1.11
2 Glycogen phosphorylase 2.4.1.1
R
3 Hexokinase 2.7.1.1
PEP 7 Pyruvate 3' Hexokinase (liver) 2.7.1.1
4 Glucose 6-phosphatase 3.1.3.9
Acetyl
R Insulin R CoA 5 6-Phosphofructokinase 2.7.1.11
9 8 6 Fructose 1,6-bisphosphatase 3.1.3.11
Cortisol
Glucagon 7 Pyruvate kinase 2.7.1.40
8 Pyruvate carboxylase 6.4.1.1
Oxalo- Oxalo-
acetate acetate 9 PEP carboxykinase (GTP) 4.1.1.32

B. Fructose 2,6-bisphosphate
Insulin Citrate, PEP
5

10a
P ATP
Fructose 6- Fructose 2,6- Fructose 1,6-
phosphate bisphosphate bisphosphate
ADP

10b
6
Insulin cAMP Glucagon

10a 6-Phosphofructo-2-kinase 2.7.1.105 10b Fructose 2,6-bisphosphatase 3.1.3.46

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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