Page 252 - Color Atlas of Biochemistry

Transcription 243

A. Transcription and maturation of RNA: overview
ATP, GTP, CTP, UTP Transcription Maturation

28S rRNA
Polymerase I 45S rRNA 18S rRNA
5.8S rRNA
hnRNA mRNA
Polymerase II snRNA-
precursors snRNA
α-Amanitin
5S rRNA
Polymerase III Precursors tRNA
snRNA
DNA
DNA-directed RNA
polymerase 2.7.7.6

B. Organization of the PEP-CK gene
Translation
Transcription Translation Exon Intron end (TAA)
start start (ATG)
Transcription
100 Bases end

5' 3' DNA
Promoter
region Transcription

5' 3' 3' hn RNA

RNA maturation

5' 3' Poly-A sequence mRNA
Cap
AUG UAA

C. Process of transcription
TATA-Box
...TATAAA.. Transcription start ..AATAAA.. Polyadenylation
sequence
3'
5'
1. Basal transcription complex

3'
5'

2. RNA Polymerase II Template strand
P Elongation
P P
3'
5'
3.
Cap
P
Termination
P P
3'
5'
4.
hnRNA

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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