Page 280 - Color Atlas of Biochemistry

Digestion 271

A. Formation of hydrochloric acid

Interstitial Parietal cell Lumen of the stomach
fluid
Peptides
H O A P Pepsino- Pepsins
2
PP gens 3.4.23.1-3
CO 2 CO 2 1 Native
protein
K K

Anion H H
exchanger 2

A H Cl
HCO 3 PPP ≈ 0.1 mol · l -1
HCO 3
Cl Cl
Cl Chloride channel Denatured
protein
Micro-organism

2
1 Carbonate dehydratase 4.2.1.1 [Zn ] 2 H /K -exchanging ATPase 3.6.1.36
B. Zymogen activation

Small bowel Mucosal cell Entero- Pancreatic secretion
peptidase
3.4.21.9
Trypsin
3.4.21.4 Various
zymogens
Trypsinogen

Trypsin inhibitor

Activated digestive Zymogens: Premature
enzymes Procarboxypeptidases trypsin
activation
Proelastase
Chymotrypsinogen
Prophospholipase A
Digestion 2
Trypsinogen Blocked trypsin

C. Fat digestion
1 Triacylglycerol lipase 3.1.1.3 Enterocyte
1
Micelle Resorption
C-terminal
domain 1

Monoacyl-
Colipase
glycerol
Bile salt
Phospholipid
Triacylglycerol

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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