Page 278 - Color Atlas of Biochemistry
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Digestion      269


                 A. Digestive juices


                 Saliva                                                          Endoenzyme
                 Daily secretion 1.0–1.5 l
                 pH 7                                                            Exoenzyme
                 Water             Moistens food
                 Salts
                 Mucus             Lubricant                                  Compo-      Function
                 Antibodies        Bind to bacteria                           nents       or substrate
                 α-Amylases (3.2.1.1) Cleave starch
                 Lysozyme (3.2.1.17) Attacks bacterial cell walls
                                                             Gastric juice
                                                             Daily secretion 2–3 l
                                                             pH 1
                 Bile                                        Water
                 Daily secretion 0.6 l                       Salts
                 pH 6.9–7.7                                  HCl                      Denatures proteins,
                 Water                                                                kills bacteria
                 HCO 3             Neutralizes gastric juice  Mucus                   Protects stomach lining
                 Bile salts        Facilitate lipid digestion  Pepsins (3.4.23.1-3)   Cleave proteins
                 Phospholipids     Facilitate lipid digestion  Chymosin (3.4.23.4)    Precipitates casein
                 Bile pigments     Waste products            Triacylglycerol lipase (3.1.1.3) Cleaves fats
                 Cholesterol       Waste product             Intrinsic factor         Protects vitamin B 12



                 Pancreatic secretions
                 Daily secretion 0.7–2.5 l
                 pH 7.7 (7.5–8.8)
                 Water
                 HCO 3                           Neutralizes gastric juice
                 Trypsin (3.4.21.4)              Proteins
                 Chymotrypsin (3.4.21.1)         Proteins
                 Elastase (3.4.21.36)            Proteins
                 Carboxypeptidases (3.4.n.n)     Peptides
                 α-Amylase (3.2.1.1)             Starch and glycogen
                 Triacylglycerol lipase (3.1.1.3)  Fats
                 Co-Lipase                       Cofactor for lipase
                 Phospholipase A  (3.1.1.4)      Phospholipids
                              2
                 Sterol esterase (3.1.1.13)      Cholesterol esters
                 Ribonuclease (3.1.27.5)         RNA
                 Deoxyribonuclease I (3.1.21.1)  DNA



                 Secretions of the small intestine
                 Daily secretion unknown
                 pH 6.5–7.8
                 Aminopeptidases (3.4.11.n)      Peptides
                 Dipeptidases (3.4.13.n)         Dipeptides
                 α-Glucosidase (3.2.1.20)        Oligosaccharides
                 Oligo-1,6-glucosidase (3.2.1.10)  Oligosaccharides
                 β-Galactosidase (3.2.1.23)      Lactose
                 Sucrose α-glucosidase (3.2.1.48)  Sucrose
                 α, α-Trehalase  (3.2.1.28)      Trehalose
                 Alkaline phosphatase (3.1.3.1)  Phosphoric acid esters
                 Polynucleotidases (3.1.3.n)     Nucleic acids, nucleotides
                 Nucleosidases (3.2.2.n)         Nucleosides
                 Phospholipases (3.1.n.n)        Phospholipids




           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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