Page 340 - Color Atlas of Biochemistry
P. 340
Kidney 331
A. Renal hormones
Differentiation
Maturation
Stem cell
Erythrocyte
Calcidiol 1-monooxygenase
OH 1 [heme P450]1.14.13.13
25
2 Renin 3.4.23.15
Erythropoietin
18.4 kDa Peptidyl-dipeptidase A
3 2
Hormone [Zn ] 3.4.15.1 (ACE)
CH 2
pO
3 1 2
HO OH Blood
Angiotensinogen
Prorenin 57 kDa
Calcitriol Calcitriol
Renin Renin 2
42 kDa
Parathyrin 1
Enzyme
Digestive Angiotensin I
tract Calcidiol
Kidneys
Bones 3
Calcidiol
from liver Angiotensin II
Hormone
B. Renin angiotensin system
Na
Angiotensinogen Blood pressure Effects
from liver
Kidneys:
2 Na retention
H O retention
2
Protein Residual
protein
Decapeptide Angiotensin I Brain:
Release of
ACE inhibitors 3 corticotropin
and adiuretin,
Dipeptide Thirst
Octapeptide
DRVYIHPF Angiotensin II
Adrenals:
Aldosterone
Hormone
production
4
Blood vessels:
Vasoconstriction
Blood pressure
4 Peptidases 3.4.n.n Degradation products
Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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