Page 342 - Color Atlas of Biochemistry
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Muscle      333


                 A. Organization of striated muscle
                                                            Muscle                                Tendon

                  Bundle of muscle fibers




                                                                                           Nucleus





                    Z  Sarcomere  Z          Z
                                                                                            Muscle fiber



                     H zone        A band   I band
                                                                 Z         H         Z line
                 Myofibril



                Troponin       Actin     Tropomyosin



                       Thin actin filament
                                                                                                     NH 3
                                                                              150 nm
                                                                            Small subunits
                                                             OOC
                                                             OOC
                                                                                Globular head
                       Thick myosin filament                             Myosin molecule
                                                                                                     NH 3

                 B. Mechanism of muscle contraction

                                                                                    Thin
                                 Center of the                                      filament
                                 sarcomere
                                                                                    Thick
                                                                                    filament

                       P
                                         5           Myosin head relaxed          1
                   A
                      P P
                                                                                                     Actin


                                Power stroke               A
                                                              PP P
                                                             ATP
                                                                                                   Myosin
                                                                             H O
                                                                              2
                                     4                                                2


                                           Contact                                     Myosin head contracted


                                                              3




           Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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