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CHAPTER 21

               OmniFlex: omnidirectional flexible


               hand-held endoscopic manipulator with

               spheroidal joint


                                                 1
                                                                                      1
                                                                        1
               Hritwick Banerjee 1,2 , Low Rui Qi , Joel Tan Xian Zheng , Bryan Chua ,
                                1
               Pham Tan Hung and Hongliang Ren       1
               1                                                                     2
                Department of Biomedical Engineering, National University of Singapore, Singapore, Max Planck
               Institute for Intelligent Systems, Stuttgart, Germany


               In this chapter, we discuss and design a flexible endoscopic manipulator, OmniFlex, capable of
               omnidirectional rotation that can be actively controlled intuitively. Biopsy forceps with precision
               control is important, so it is essential to have flexible forceps that can detach from the endoscopic
               distal end to reach the area of the lesion. With this, a large field of operation of the area can be
               maintained by the practitioner, hence increasing the precision. The tool bends according to the
               curvature of the flexible endoscopic manipulator. Because of its compliant nature, the forceps rely
               on the endoscopic manipulator for support. OmniFlex promotes ease of usage with one-hand
               intuitive ball and socket control and omnidirectional curvature. Shape-lock ability, on the other
               hand, enables multitasking capability. No twisting of the prototype is required to touch hard to
               reach the targeted spot. The curvature angle can be about 150 degrees in all four directions.

               21.1 Introduction


               21.1.1 Nasopharyngeal carcinoma: origin and anatomy

               Nasopharyngeal carcinoma (NPC) originates in the nasopharynx, the area behind the nose
               and near the base of the skull [1]. Healthy cells proliferate in an orderly manner. In the case
               of cancer, cancer cells are unable to stop proliferating and dividing, which will eventually
               lead to the formation of a lump or tumor [2,3]. Therefore in nasopharyngeal cancer, cancer
               cells are formed in the tissues of the nasopharynx. The most common method of diagnosis
               is by collecting biopsy samples using nasal endoscopy (NE) [4]. Such a procedure will
               require an operator to insert a flexible endoscopic manipulator into the nose. A camera
               located at the distal end of the flexible endoscopic manipulator can survey the nasopharynx
               for tumors. The operator conducting operation may collect a tissue sample by passing a

               Flexible Robotics in Medicine.
               DOI: https://doi.org/10.1016/B978-0-12-817595-8.00022-5  473
               © 2020 Elsevier Inc. All rights reserved.
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