Page 351 - Glucose Monitoring Devices

358 Index

Closed-loop insulin delivery system (Continued) observational trials, 140e141
continuous subcutaneous insulin infusion (CSII) operational advantage, 138
pumps, 328 pregnancy data, 142e143
controlled research environments, 334e335 quality of life data, 143
FDA approved simulator, 334 randomized controlled trials, 140e142,
free-living home assessments, 335 146te147t
fully closed-loop (FCL) system, 334 real-time CGM (RT-CGM), 140e142
hybrid closed-loop systems, 334 retrospective, 140
MiniMed 670G system Senseonics, 150
adjunctive agents, 339 sensor-augmented pump (SAP), 151e152
auto mode, 337e338 Continuous glucose monitoring (CGM) system,
bihormonal systems, 339 20e21, 53, 275. See also Minimally
challenges, 339e340 invasive continuous glucose monitoring
forced system, 338 (CGM) sensor calibration
Guardian sensor 3, 336e337 advances, 111
hotel-based study, 335e336 automated closed-loop control, 159
hybrid closed-loop systems, 339e340 blood glucose (BG) fluctuations, 241e242
insulin pump, 337 calibration errors, 241e242
3-month single-arm study, 336 challenges, 241
Nightscout Project, 340e346 clinical accuracy
outpatient studies, 335e336 CGM data point represention, 161f
patient considerations, 346 continuous glucose-error grid analysis
pediatric population, 336 (CG-EGA), 161e162
research unit-based study, 335 euglycemia, 164e165
retrospective analysis, 338 hyperglycemia, 164e165
predictive low glucose suspend (PLGS) system, hypoglycemia, 164e165
331e332 point accuracy-error grid analysis (P-EGA),
primary control algorithms, 333 161e162, 162f
registry data, 328 rate-error grid analysis (R-EGA), 163e164,
transitional environments, 335 164f
Consensus error grid (CEG), 35, 45e46, 46f commercial systems
Continuous glucose-error grid analysis Abbott Freestyle Libre flash glucose monitor,
(CG-EGA), 161e162 127
Continuous glucose monitoring (CGM) device Dexcom G6 CGM, 127e128
alarm feature, 139 Eversense CGM System, 128e129
clinical application, 139 feature comparison chart, 129f
Dexcom G6 Mobile system, 145e149 implantable sensors, 126e127
efficacy, 140e143 Medtronic Guardian Connect, 128
evolution, 136 transcutaneous sensor-based systems, 126
flash glucose monitoring system disposable sensor, 111
Freestyle Librelink App, 150e151 error mitigation, 241e242
HART CGM study, 151 glucose transduction technologies
IMPACT trial, 150e151 electrochemical glucose oxidase sensor, 116
glycemic control, 138 enzymatic, electrochemical-based glucose
glycemic load, 138 sensors, 113e115
inpatient, 152 fluorescent glucose sensors, 117
limitations microneedle-array sensors, 116e117
device dependent, 144e145 nonenzymatic, optical-based sensors, 114e115
healthcare provider dependent, 144 tissue-integrating sensors, 117
user dependent, 143e144 glycemic variability, 111
Medtronic, 149 interstitial glucose (IG) fluctuations, 159e160
Medtrum, 149 measurement error modeling