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Upper-Limb Prosthetic Devices                                217


              to “feel” where his or her prosthesis is without seeing it. The information
              comes integrative to the amputee by using the remaining afferent (sensory)
              pathways which are now integrated with the prosthesis and give us an EPP
              type of control which we know from the past that has advantages over other
              prosthesis control topologies (Childress, 1997, 1998; Doubler and
              Childress, 1984a).
                 For upper-limb amputees, the protocol, and device are part of the
              Osseointegrated Human-Machine Gateway (OHMG) (Ortiz-Catalan
              et al., 2014a). The osseointegration implant provides also the gateway or
              “corridor” for intramuscular EMG electrodes to be placed in the muscles
              and the wires to come out (Ortiz-Catalan et al., 2013, 2014a). OHMG
              should be viewed as a platform. Fig. 19 describes all the details of the OHMG
              platform.
                 A modified OHMG platform could be used in the future for lower limb
              Osseointegration prostheses.
                 As we mentioned before, one of the benefits of all Osseointegrated pros-
              theses is the Osseoperception provided by the receptors and the direct
              mechanical linkage provided. Therefore, the OHMG, facilitates the integra-
              tion (and thus “Integrum” is a good name) of the motor and sensory aspects
              needed for upper-limb prostheses, eliminating the need for wireless
              interfaces.
                 All the potential benefits and advantages of osseointegration do not come
              without problems. The biggest problem of this technique is its long lasting
              battle with bacteria at the skin interface and its unknown long-term impact
              on the quality of the bone fixture (Lenneras et al., 2017). Therefore, long-
              term studies are needed. Radiologically found endosteal bone resorption
              accompanied with pain at loading might be associated with potential weak-
              ness of the bone fixture (Lenneras et al., 2017). Different osseointegration
              research groups are taking nine different engineering variants of the implant
              designs and materials in order to achieve a stable mechanical interface
              between the bone and the implant (Thesleff et al., 2018). The prominent,
              the ORPA treatment protocol, which involves the traditional surgical tech-
              nique from Sweden and rehabilitation protocol, involves a threaded
              titanium abutment screwed into the medullary cavity of the bone
              (Fig. 20) and a long rehabilitation phase. This treatment protocol has been
              adapted for transhumeral, transradial, thumb, or finger amputations of the
              upper limb (Thesleff et al., 2018).
                 More comparative details on the different surgical techniques and
              implant systems are given in Thesleff et al. (2018).
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