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268                             Georgios A. Bertos and Evangelos G. Papadopoulos













































          Fig. 19 Natively innervated and surgically reinnervated residual thigh muscles. Poste-
          rior views of the anatomy of the upper thigh show natively innervated hamstring mus-
          cles (Panel A) and nerve transfers performed during targeted muscle reinnervation
          (TMR) surgery (panel B) in the residual limb. (From Hargrove, L.J., Simon, A.M., Young, A.J.,
          Lipschutz, R.D., Finucane, S.B., Smith, D.G., Kuiken, T.A., 2013. Robotic leg control with EMG
          decoding in an amputee with nerve transfers. N. Engl. J. Med. 369(13), 1237–1242. https://
          doi.org/10.1056/NEJMoa1300126.)



          was sewn over the motor area of the long head of the biceps femoris. After a
          few months, the TMR was successful and the amputee could voluntarily
          activate the motor areas that were reinnervated, leaving extra control sites
          for prosthesis control, which were used together with prosthesis sensors
          to a pattern recognition algorithm for controlling different states of prosthe-
          sis (walking, ascending and descending the stairs, ramps, and reposition the
          leg while seated).
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