Page 249 - Industrial Ventilation Design Guidebook

2 I 0 CHAPTER 5 PHYSIOLOGICAL AND TOXICOLOGICAL CONSIDERATIONS

TABLE 5.7 Predictive Equations for Static Lung Volumes and Dynamic
26
Pulmonary Function

Parameter Gender Prediction Equation
Vital Female 0.0404H n 099 A - 1 35 - HZil 0 00878 4-4-0 5673 Ino- A 0.5509 + on -, 4 .
Z-...K.,'
\J , V,/UOZ,O jTl T^ w.~?Vf / ,./ HJfofT
— ^/.v/iZj/l
~~
capacity H W
w + l.U^U6
Male 0.0481 H 00104 i gi 1-489^. 0 Q069 A i 05191 log 4 0.6347 , pf) .
H
Q
Residual Female 0.032H- 0 00° 4 3 0 2.1684 0 0037/1 4 | OOlS5logA 9-2457 -^
19M 4
+1
w
volume H
Male 0.027H - 0.01 7 A - 3.447 - 23637 - 0.00338 + 0.63871ogA - • 10.5711 06Q/|
H w
1 71 14 3 06()1
+ 1 3667
Total lung Female 0.079H- 0 (IDS 749 i/i-J^r 0003904 i 0 3481 Inc- 4 •^ +1.366,
capacity o
00154 91 6"? 1/3.61 A nnc^'i 4
, 0 cTQTir.^ 4
Male 0.094H- V./.V/ i ^» /i — / . 1 O / — ————— — \s , \J\JJ O J. y^ T^ L/.>.J £*s L* lUg,/i M1M 4.1 7155
+J 21X
ri W ' '
Forced Female 3.95H- 0.025 A - 2.60
expired
volume,
1 s* Male 4.30H- 0.029A-2.49
Forced vita! Female 4.43H- 0.026A-2.89
capacity*
Male S.76H- 0.026 A -4.34
Peak Female 5.5QH- 0.030A-1.11
expired
flow*
Male 6.14H- 0.043A + 0.15
A = age (years); H = height (cm); W = weight (kg)
"Health Survey for England (1996)
http://www.official-documents.co.uk/document/doh/survey 96/ehch3.htm#3.7

Forced expiration is commonly used to assess pulmonary function in both
healthy and impaired individuals. Static measures of lung volumes (TLC, V T,
FRC) fail to detect dynamic changes in pulmonary function that are attribut-
able to disease (e.g., asthmatic airway constriction). Obtaining maximum ex-
piratory flow-volume (MEFV) curves (Fig. 5.21) permits derivation of key
parameters in detecting changes in lung function.
Forced vital capacity (FVC) quantifies the maximum air volume ex-
pired following a maximal inspiration and is one of the basic measures of
analyzing flow changes such as reduced airway patency observed in
asthma. To measure FVC, an individual inhales maximally and then ex-
hales as rapidly and completely as possible. FVC primarily reflects the elas-
tic properties of the respiratory tract. The gas volume forcibly expired
within a given time interval, FEV r (where t is typically one second, FEVj 0)