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                                         Part III: Comparing Many Means with ANOVA
                                         Setting Up the Two-Way ANOVA Model
                                                    The two-way ANOVA model extends the ideas of the one-way ANOVA model
                                                    and adds an interaction term to examine how various combinations of the
                                                    two factors affect the response. In this section, you see the building blocks of
                                                    a two-way ANOVA: the treatments, main effects, the interaction term, and the
                                                    sums of squares equation that puts everything together.
                                                    Determining the treatments
                                                    The two-way ANOVA model contains two factors, A and B, and each factor
                                                    has a certain number of levels (say i levels of factor A and j levels of factor
                                                    B). In the drug study example from the chapter intro, you have A = drug
                                                    dosage with i = 1, 2, or 3 and B = number of times taken per day with j = 1 or
                                                    2. Each person involved in the study is subject to one of the three different
                                                    drug dosages and will take the drug in one of the two methods given. That
                                                    means you have 3  2 = 6 different combinations of factors A and B that you
                                                                    *
                                                    can apply to the subjects, and you can study it in the two-way ANOVA model.
                                                    Each different combination of levels of factors A and B is called a treatment in
                                                    the model. Table 11-1 shows the six treatments in the drug study. For exam-
                                                    ple, Treatment 4 is the combination of 20mg of the drug taken in two doses of
                                                    10mg each per day.
                                                      Table 11-1   The Six Treatment Combinations for the Drug Study
                                                      Amount             One Time/Day         Two Times/Day
                                                      10mg               Treatment 1          Treatment 2
                                                      20mg               Treatment 3          Treatment 4
                                                      30mg               Treatment 5          Treatment 6
                                                    If factor A has i levels and factor B has j levels, you have i  *  j different combi-
                                                    nations of treatments in your two-way ANOVA model.


                                                    Stepping through the sums of squares

                                                    The two-way ANOVA model contains three terms:
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