Page 84 - Modern Derivatization Methods for Separation Sciences

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antiparasitic drugs which are potent broad-spectrum agents at very low dosage levels. Avermectins have
been used for veterinary medicine, especially for antiparasitic agents for livestocks or pesticides for
agricultural insect and mites. The former includes ivermectin, doramectin and moxidectin, while the
latter includes avermectin B and milbemectin. The usage of these drugs differs, but these avermectins
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have similar chemical structures consisting of a 16-membered macrocyclic lactone ring. Thus common
derivatization method

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