Page 309 - Multidimensional Chromatography

304 Multidimensional Chromatography

C18; C18 UV 34
extraction
Melengestrol bovine tissue liq–liq phenyl
silica; silica UV 31
acetate extraction
Table 11.1 (continued)

Sample First
Subsequent
Analyte(s) Sample matrix preparation a LC mode b
LC mode(s) b Detection c Reference
Methandrostenolone equine liq–liq phenyl
C18; C8 UV and 30
and its metabolites plasma/urine extraction
MS–MS
Metyrapone human liq–liq silica
Chiralcel OJ UV 42
plasma/urine extraction

Phenyl- human liq–liq ion-pair
C18 UV 36
propanololamine plasma/urine extraction C18
Probenicid rat plasma deproteination C18
ion-pair C18 UV 63
Propanolol human plasma liq–liq ion-pair
C18 UV 35
extraction C18
Methotrexate human urine SPE AIEX
C18 UV 26
Remoxipride human plasma liq–liq CN
C18 EC 17
metabolite extraction

Ro 23-7637 dog plasma SPE CIEX
C18 UV 27
Ro 24-0238 human plasma SPE CIEX
C8 UV 25
Ropivacaine human plasma ultrafiltration C8
CIEX UV 24
Sameridine human plasma ultrafiltration C18
CIEX; CIEX UV 16
TCV-116 and human liq–liq C18
C18 Flu 64
its metabolites serum/urine extraction

Tipredane rat urine none CN
C18 UV 18
metabolites