Page 311 - Multidimensional Chromatography

306 Multidimensional Chromatography

Chiralcel OJ
Mefloquine human plasma/whole liq–liq CN
silica; UV 52
blood extraction
(S)-
naphthylurea
Metoprolol human plasma SPE AGP
C18; C18 Flu 54
Metyrapol human liq–liq silica
Chiralcel OJ UV 42
plasma/urine extraction
Table 11.1 (continued)

Sample First
Subsequent
Analyte(s) Sample matrix preparation a LC mode b
LC mode(s) b Detection c Reference
Oxazepam human plasma SPE BSA-silica
C18; C18 UV 54
p-HPPH d rat liver liq–liq C18
C18 with UV 46
microsomes extraction
L-prolinamide
Pimobendan and its human plasma liq–liq extraction silica
Chiralcel OD UV 48
metabolite

Terbutaline human plasma SPE phenyl
-CD C18 EC 51
human plasma SPE AGP
C18; C18 EC 54
human plasma SPE phenyl
-CD EC or MS 57
Verapamil and human plasma liq–liq C18
Ovomucoid UV 50
its metabolites extraction
Endogenous Compounds
Creatinine human buffer dilution SEC
SEC; CIEX UV 58
serum/urine
CIEX;
Glutathione cytosol of human homogenization, affinity
C8 or C18 UV 11
S-transferases lung tissue centrifugation
Hydroxy- human urine SPE PRP
C18 EC 59
deoxyguanosine
Hydroxytryptamine rabbit blood centrifugation CIEX