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12  Transgenic Approaches to Enhance Phytoremediation of Heavy Metal-Polluted Soils  261

            promoting mobilization of metals in soils. Efforts should thus be devoted to assess
            the effect that modifications for enhanced secretion of metal-complexing root
            exudates, ideally combined with implementation of the cognate metal-complex
            transport mechanism, would have on phytoextraction of soil metals. Conversion
            of immobile metals to their bioavailable forms in soils is largely dependent on the
            activity of soil microflora. Thus, modification of bacteria and fungi for secretion of
            protons and metal ligands can be also taken into account.
              Genetically modified plants may endue remediation of heavy metal contamina-
            tion with obvious benefits, yet some would question their techno-economic per-
            spective and environmental safety. The best way to determine the true
            phytoremediation potential of genetically modified plants is by conducting field
            trials (Ban ˜uelos et al. 2005, 2007; Van Huysen et al. 2004), which must be also
            designed to assess risks.




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