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01 (001-030B) chapter 01  1/29/02  4:48 PM  Page 5






                               Framing the Problem                                          5


                                   ple. I think just focusing people on that has allowed me to
                                   add value.
                                   Many highly successful organizations don’t apply structured
                               thought even to their core competencies, as Paul Kenny describes
                               at GlaxoSmithKline:

                                   From a scientific point of view, a lot of the research organi-
                                   zation is rather serendipity led: you invest in research, you
                                   may have a direction, but often that direction will change
                                   as a result of information you find. Some of the best drugs
                                   on the market today were found more by luck than by
                                   design. Then, thinking back, we realize that we could have
                                   redesigned these clinical trials in a way to shape the product
                                   more appropriately for the market. There are concrete exam-
                                   ples of ways to increase value by making more-commercial
                                   marketing decisions earlier on in the pipeline, and designing
                                   products from the very beginning to have the right charac-
                                   teristics, rather than just letting them evolve from the R&D
                                   pipeline however they emerge.

                                   If structured thinking is hard to find at GE and GlaxoSmith-
                               Kline, two of the world’s most respected and successful companies,
                               one can imagine that it may be a pretty rare coin in many
                               organizations.
                                   Further complicating matters, the corporate cultures of some
                               organizations have been imbued with the wrong types of structure.
                               In another example from GlaxoSmithKline, a linear, deductive
                               thought process got in the way of sound decision making:

                                   We have a project leader who wants to switch his drug from
                                   its current twice-a-day formulation to a once-a-day formu-
                                   lation. The drug is at an early stage in research, and it’s a
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