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References 61

whole-cell environment, as the majority of successful case studies are based on
such processes (either in a fully in vivo format or in combination with an in vitro
biocatalyst). In this context, the enzyme group is a highly compatible ‘‘reagent’’
for the combination with other biocatalysts. This can be attributed to the high
functional and/or stereochemical selectivity of such proteins. Consequently, it can
be expected that monooxygenases will become a versatile tool in the armory of the
diverse catalytic systems to be utilized for the construction of nonmetabolic reaction
cascades as well as mini-metabolic pathways en route toward true biocatalytic cell
factories.

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