Page 107 - Control Theory in Biomedical Engineering

Without control
With control
0.9
1
0.6
0.8
0.7
1.3
0.4
0.5
1.1
1.2
Effector cells, E(t)
30 0.3 30 25 20 15 10 5 0 Time (days) 2 1.8 1.6 1.4 1.2 1 0.8 0.6 Imunotherapy control, W(t) 0.4 0.2 0 30 30 25 20 15 10 5 0 Time (days) treatment the chemotherapy and after (3), before of system 10. day by eradicated be can
With control Without control the tumor cells and effector cells population
25 25
20 20 cells’ tumor
15 Time (days) 15 Time (days) populations of the
10 10 that shows
5 5 It w(t).

0 0 Numerical simulations of and
300 250 200 150 Tumour cells, T(t) 100 50 0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 Chemotherapy control, V(t) 0.2 0.1 0 v(t)

Fig. 2 controls with