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336                                                Borna Ghannadi et al.


          rehabilitation robot. In Ding et al. (2010), a musculoskeletal upper extremity
          model (without including muscle dynamics) was used to implement a
          model-based assistive controller for a full-body rehabilitation exoskeleton.
             At the University of Zurich (Switzerland), model-based arm weight
          compensation is used inside the controller for “ARMin V” (sem-
          iexoskeleton). The results of this study showed that with active model-based
          gravity compensation, the patient’s effort will drop significantly.
             The biological control structure of the CNS can be represented by an
          nonlinear model predictive control (NMPC) with receding horizon. In
          the NMPC, a forward dynamics model is used to generate gross optimal
          movements, and feedback information is used for fine-tuning. NMPC is
          used in a variety of applications in biomechanics (Mehrabi et al., 2017)
          and automotive control (Maitland and McPhee, 2018). Recent progress
          in the development of NMPC motivated researchers at the University of
          Waterloo (Ontario, Canada) to control a rehabilitation robot using NMPC
          with a nonlinear dynamic HRI model (Ghannadi et al., 2017). In this
          research, the HRI model was confined within an NMPC of the single-robot
          manipulandum (which is designed and developed by the Toronto Rehabil-
          itation Institute (TRI) and Quanser Consulting Inc.). The proposed con-
          troller used a musculoskeletal model of the upper extremity to predict
          human movements and muscle activations (Mehrabi et al., 2017), thereby
          providing optimal assistance to the patient. In this study, the controller suc-
          cessfully predicts the muscular activations in model-in-the-loop simulations.
             Model-based strategies for rehabilitation are more appealing than the
          triggered-passive methods since they do not require patient preparation
          for sensor attachment. However, the models should be identified within
          an acceptable accuracy to ascertain the validity of bio-inspired information.
          This accuracy should be achieved with a proper parameter identification
          procedure that is done with the use of bio-sensors in pretests with the robot.
          Thus, having a systematic approach for pretests and developing powerful
          tools for parameter identification is a key element in the success of these
          methods.



               8 CONCLUSION

               In this chapter, a review of upper extremity rehabilitation robots was
          presented, considering their mechanical design, type of training, form of
          rehabilitation, and control scenarios. Then, recent enhancements in the field
          of rehabilitation robotics were introduced.
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