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L1644_C04.fm  Page 140  Tuesday, October 21, 2003  3:13 PM









                             Morbidity
                             This effect concerns the following primary and secondary pollutants: NO , SO ,
                                                                                               2
                                                                                          x
                             NH , CO, nitrate aerosol, sulphate aerosol and PM10. Possible impacts are, among
                               3
                             others, hospital visits, bronchodilator use and chronic cough.
                             Mortality
                             The effect of mortality can be expressed by fatal cases or years of life lost (YOLL),
                             as previously explained in Chapter 3. However, since in recent years researchers
                             have moved from studies based on fatal cases to YOLL (EC, 1995; EC 2000), YOLL
                             is used as endpoint in this study.  Table 4.4 illustrates the highly important E-R
                             functions that use YOLL as endpoint.

                               For example the additional YOLL by sulphates are calculated in the following way:

                                             0.0012 YOLL/(mg/m3) * 0.00082 mg/m3)/
                                         functional unit * 423,000 pers.* 0.75 adults/pers. =
                                                      0.312 YOLL/ TWh


                              where  Dc = 0,00082 (µg/m ) concentration increase/functional unit
                                                     3
                                   Pop. = 423,000 pers. (population expressed as persons in region considered)
                                  adults = 0.75 adults/pers. (percentage of population which age above 18 years)

                                Caution must be exercised in interpreting every epidemiological study because
                             any number of confusing variables may lead to invalid conclusions. For example, a
                             study may be biased because workers are compared with nonworkers (workers are
                             usually healthier) or because relative rates of smoking have not been accounted for,
                             or other variables that may be the actual causal agents may not even be hypothesized



                             TABLE 4.4
                             Mortality Functions Expressed in YOLL Due to Concentration Increments
                             (µg/m ) (IER, 1998)
                                  3
                              Receptor     Category     Pollutant               Formula
                             Adults: Percentage of Population with Age above 18

                                         'chronic' YOLL  PM10 /         0.00072 * Dc * Pop. * adults
                                                         Nitrates
                                                        Sulphates       0.0012 * Dc * Pop. * adults
                                          'acute' YOLL    SO 2      0.0719 * Dc * Pop. * b_m /100 * adults
                                                         PM10 /      0.04 * Dc * Pop. * b_m /100 * adults
                                                         Nitrates
                                                        Sulphates   0.0677 * Dc * Pop. * b_m /100 * adults
                                                                    0.0648 * Dc * Pop. * b_m /100 * adults
                                                          NO x
                             b_m: baseline mortality
                             Source: IER (1998)


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