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140        Six SigMa  DemystifieD



                     TAble­6.6­ aNOVa for Folded DOE (after Removal of Terms)

                                  df           SS           MS            F            Significance
                                                                                       F
                     Regression    4           4297.25      1074.313      149.2336     1.67E	–	09
                     Residual     11              79.1875      7.198864
                     Total        15           4376.438

                    Note:	df	=	degrees	of	freedom;	SS	=	sum	of	squares;	ms	=	mean	square


                        error. Pure error is calculated as 68.5 using the sum-of-squares deviations
                        between each observation and the mean at that condition. The  lack- of- fit error
                        is calculated as 10.6875 using the difference between the total (residuals) error
                        and the pure error. The F statistic is calculated as







                          The calculated F value for the lack of fit is less than the critical value
                        F 0.05,3,8  of 4.07, so the null hypothesis that the model is adequate cannot be
                        rejected. In this case (failing to reject that the model is adequate), the signifi-
                        cance of the fitted model can be tested using the F statistic applied to the
                        residuals, as in Table 6.6. If the residuals are small (as demonstrated by signifi-
                        cance of the regression term) and pass the other general tests described in the
                        “Residuals Analysis” section of Part 3, then the model would seem to fit the
                        data adequately and can be used to determine optimal combinations for
                        the response.
                          If the  ack- of- fit test is rejected, then the model should be updated with
                                l
                        additional main factors and interactions or  higher- order terms. A quick test
                        for surface curvature (described in Part 3) helps to rule out  higher- order
                        terms.
                          Recall that the power of a statistical test is the probability of rejecting the
                        null hypothesis when the null hypothesis is false. In this case, the null hypoth-
                        esis is that the coefficients of the regression are zero; the alternative hypothesis
                        is that at least one of the coefficients is nonzero.
                          Minitab provides a convenient way to test our ability to estimate effects of
                        given magnitude or, conversely, to estimate the number of design replicates
                        needed to detect effects at a given power for a given experimental design.
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