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254        Six SigMa  DemystifieD


                          Saturated designs refer to special cases of FFDs where only the main factors
                        can be estimated. In a saturated design, the minimum number of experimental
                        conditions (1 + p) is used to estimate the p main factors. For example, use a 2 3–1
                        design to estimate three factors in four runs, a 2 7–4  design to estimate seven
                        factors in eight runs, and a 2 15–11  design to estimate 15 factors in 16 runs. In
                        saturated designs, the main factors are all confounded with two-factor interac-
                        tions. In addition, we have no “extra” runs to estimate error, so we cannot deter-
                        mine which parameters are significant to the regression. We can only calculate
                        the parameter effects, which provide the coefficients of the regression equation.
                        Generally, we will add at least one additional run (a degree of freedom) to the
                        saturated design, resulting in p + 2 runs, to allow an estimate of experimental
                        error and resulting significance of the model terms. A center point [where each
                        factor is set to the midpoint between its high (+1) and low (–1) condition] can
                        be used to provide a rough estimate.
                          It should be clear that the fewer parameters we need to estimate, the less
                        costly the experiment will be to run. Often at least one factor in a design is
                        statistically insignificant. If, after collecting and analyzing the data, we can
                        remove that factor from the analysis, we are left with a replicated data set that
                        provides an estimate of error and better estimates of the remaining factors.
                          See also “Plackett-Burman Designs,” “John’s ¾ Designs,” and “Central Com-
                        posite Design” in the Glossary and “Response Surface Analysis” topic elsewhere
                        in Part 3.

                                           Factorial Designs


                        Minitab

                        Use Stat\DOE\Factorial\Create Factorial Design\2-level factorial (default genera-
                        tors). Specify Number of Factors.
                        Select the “Designs” button to select a design. Replicated screening designs are
                        usually preferred, so select two corner point replicates; blocks (see “Blocking Fac-
                        tor” in the Glossary) are not generally needed for an initial screening design; center
                        points are optional. Select the “Factors” button to specify Numeric (i.e., quantita-
                        tive) or Text (i.e., qualitative) and real experimental values for each factor level.

                        Use the “Options” button to randomize experimental trials.
                        For example, a  /  fraction two-level replicated design (8 runs × 2 replicates =
                                      1
                                       8
                        16 runs) was constructed for six factors A through F. Two levels were chosen
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