Page 311 - Thermodynamics of Biochemical Reactions

Thermodynamics of Biochemical Reactions at Specified pH 311

TableForm[Transpose[calckgrime[citrateiso+nadox+h2o+de==ketoglutarate+co2tot+nadred,~5,
=
6,7,8,9),{0,.1,.25)]],Tab1eHeadings->{{111 = 0 M*m,lmI 0.10 M","I = 0.25 M"},{"pH
5'1,1'pH 6",11pH 7","pH 8"."pH 91m))]
PH 5 PH 6 PH 7 PH 8 PH 9
I=OM 0.0345704 0.50862 5.48156 55.8289 582.674
I = 0.10 M 0.108383 0.851594 6.02043 56.8417 627.221
I = 0.25 M 0.144953 0.905667 6.03701 57.1107 653.532

TableForm[(1/(8.3145l*.298l5*Log[lO]))*D[(ketoglutarate+co2tot+nadred-c~trate~so-nadox-
h20) ,pH] / .is-> (0, . 1, .25 ) / .pH-> { 5,6,7,8,9) ,TableHeadings->{ {"I = 0 M", "I = 0.10 M" , "I =
0.25 Msl),{iipH 5","pH 6","pH 7","pH 8","pH 9"))l

PH 5 PH 6 PH 7 PH 8 PH 9
I=OM -1.34729 -1.06162 -1.01433 -1.00645 -1.04494
I = 0.10 M -1.07823 -0.788138 -0.931153 -1.00411 -1.1109
I = 0.25 M -0.975816 -0.720242 -0.928031 -1.00858 -1.14667

ketoglutarate dehydrogenase

Tab~eForm~Transpose~calctrGerx[ketoglutarate+nadox+coA+h2o+de==succinylcoA+co2tot+nadre
=
d,~5,6,7,8,9},~0,.1,.25)11,TableHeadings-~{{~m1 = 0 M1l,*lI 0.10 M","I = 0.25 M"},{"pH
5","pH 6","pH 7","pH 8","pH 9"))]
PH 5 PH 6 PH 7 PH 8 PH 9
I=OM -32.2272 -32.6665 -35.7881 -40.2782 -42.8267
I = 0.10 M -32.1519 -33.08 -36.7606 -41.0722 -43.1986
I = 0.25 M -32.1464 -33.2446 -37.0834 -41.3056 -43.347

TableForm[Transpose[calckprime[ketoglutarate+nadox+coA+h2o+de==succinylcoA+co2tot+nadre
d,{5,6,7,8,9),{0,.1,.25)11,TableHeadings->{{1~1 = 0 Mrm,"I = 0.10 M","I = 0.25 M"I,{"pH
5","pH 6","pH 7","pH 8","pH 9"))]

PH 5 PH 6 PH 7 PH 8 PH 9
6 7 7
I=OM 442519. 528319. 1.86112 10 1.13869 10 3.18322 10
6 7 7
I = 0.10 M 429279. 624208. 2.75508 10 1.56857 10 3.69848 10
6 7 7
I = 0.25 M 428331. 667072. 3.1383 10 1.72338 10 3.92659 10

TableForm[(1/(8.3145l*.298l5*Log[lO]))*D[(succinylcoA+co2tot+nadred-ketoglutarate-
nadox-coA-h2o),pHI/.is->{O,.l,.25}/.pH->{~,6,7,8,9},TableHeadings->{{"I = 0 M","I =
0.10 M1l,liI = 0.25 M1l),{llpH 5m1,11pH 611,"pH 7","pH 8","pH 9"))l
PH 5 PH 6 PH 7 PH 8 PH 9
I=OM 0.0991751 -0.280585 -0.770103 -0.687272 -0.235683
I = 0.10 M 0.0252188 -0.396837 -0.811953 -0.592158 -0.237873
I = 0.25 M 0.00254914 -0.436266 -0.818663 -0.559843 -0.25715

Succinyl coA synthase