Page 315 - Thermodynamics of Biochemical Reactions

Thermodynamics of Biochemical Reactions at Specified pH 315

PH 5 PH 6 PH 7 PH 8 PH 9
7 11 16 21
I=OM 8941.45 1.79866 10 4.63551 10 3.72816 10 3.83029 10
9 13 18 24
I = 0.10 M 687894. 2.2019 10 8.04744 10 7.82684 10 1.07305 10

6 10 14 19 24
I = 0.25 M 2.91838 10 1.0769 10 4.52844 10 4.57215 10 7.00906 10

TableForm[~1/(8.3145l*.298l5*Log[lO]))*D[(3*co2tot+4*nadred+fadenzred+atg-
pyruvate-4*nadox-fadenzox-ad~-pi-5*h2o),pH]/.is-~{O,.l,.2S}/.~H-
>{5,6,7,8,9),TableHeadings->{{1rI = 0 M",glI = 0.10 M"."I = 0.25 M1l),{l'gH S","gH 6","gH
7","pH 8","pH 9"))l

PH 5 PH 6 PH 7 PH 8 PH 9
I=OM -2.97701 -3.78422 -4.85728 -4.93355 -5.12012
I = 0.10 M -3.15164 -4.02532 -4.91074 -5.034 -5.33503
I = 0.25 M -3.19064 -4.10924 -4.93937 -5.05039 -5.44262

Net reaction for glycolysis, pyruvate dehydrogenase, and the citric acid cycle

TableForm[Transpose[calctrGerx[glucose+lO*nadox+2*fadenzox+4*a~p+4*p~+8*h2o+de==6*co2to
t+l0*nadred+2*fadenzred+4*at~,{5,6,7,8,9},{O,.l,.25}ll,TableHead~ngs-~{{1~I = 0 M","I =
0.10 M"."I = 0.25 Mrm},{llpH 511,*1pH 611,"pH 7","pH 8","pH 9"))l

PH 5 PH 6 PH 7 PH 8 PH 9
I=OM -72.0125 -131.329 -201.137 -270.179 -338.639
I = 0.10 M -104.897 -166.593 -236.258 -306.076 -376.313
I = 0.25 M -115.897 -178.144 -248.124 -318.007 -388.781

TableForm[Transpose[calck~rime[glucose+lO*nadox+2*fadenzox+4*adg+4*p~+8*h2o+de==6*co2to
= 0 M","I =
t+l0*nadred+2*fadenzred+4*at~,~5,6,7,8,9~,~O,.l,.2S~ll,TableHeadin~s-~~~"~
0.10 M","I = 0.25 M"),{"pH 511,m1pH 61s,"pH 7","pH 8","pH 9">)1
PH 5 PH 6 PH 7 PH 8 PH 9
12 35 47 59
I=OM 4.13017 10 1.01782 10 23 1.72759 10 2.15268 10 2.12147 10
18 29 41 53 65
I = 0.10 M 2.38257 10 1.53315 10 2.45688 10 4.18709 10 8.4501 10
31 43 55 68
I = 0.25 M 2.01437 10 2o 1.61917 10 2.94593 10 5.15271 10 1.29175 10

TableForm[(1/(8.3145l*.298l5*Log[lO]))*D[(6*co2tot+lO*nadred+2*fadenzred+4*atg-
glucose-l0*nadox-2*fadenzox-4*ad~-4*~i-8*h2o),pH]/.is->{O,.l,.25~/.~H-
>(5,6,7,8,9},TableHeading~->{{~I = 0 M","I = 0.10 M","I = 0.25 M"), {"gH 5","pH 6"."gH
7","pH 8",I1pH 9")}1

PH 5 PH 6 PH 7 PH 8 PH 9
I=OM -9.66065 -11.3323 -12.5583 -11.8426 -12.2258
I = 0.10 M -10.2116 -11.6205 -12.3812 -12.1454 -12.6781
I = 0.25 M -10.3045 -11.7212 -12.3948 -12.1712 -12.8926