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Bhargava, R., 1 Chapter authors (Cont.):
Biomaterials Gough, Kathleen M., 125
artificial hip joint, 312–315 Gulley-Stahl, Heather, 99
micromechanics, 309–312 Hirschmugl, Carol J., 29
PS behavior, 307–309 Kaminskyj, Susan G. W., 125
spectral features, 305–307 Krafft, Christoph, 225
stress patterns, 309–315 Mattson, Eric, 29
Biomechanistic studies, 78–80 Nasse, Michael J., 29
Biomedical applications. See Raman Neugebauer, Ute, 225
microscopy for biomedical Panza, Janice, 157
applications Pezzotti, Giuseppe, 299
Biophotonic methods, 226 Popp, Jürgen, 225
BioPhotonic Scanner, 220 Potma, Eric Olaf, 319
Biotrophic fungus, 128 Pounder, F. Nell, 1
Bloembergen, Nicolas, 319 Puppels, Gerwin J., 265
Bone, 161, 288–289, 291 Ratti, Simona, 29
BPS, 239–241 Rosenthal, Ann, 29
Brain tumors, 228–236 Sharifzadeh, Mohsen, 193
Breast cancer tissue, 337–339 Sholkina, Mariya, 265
Brightfield reflectance, Sommer, Andre’ J., 99
177, 178 Stewart, Shona, 157
Bronchopulmonary sequestration Charge-coupled-device (CCD)
(BPS), 239–241 detector, 271–272
Brushite, 52 Chemical fixation, 60, 61, 71–78
Bulk tissue analysis, 64 Chemical imaging, 159
Chemical vapor deposition (CVD)
techniques, 39
C C Chemically fixed tissue, 66–68
Calcium-containing crystals in arthritic Chemometrics, 170–186
cartilage, 48–55 Chevron-type filter, 271
Cancer pixel segmentation, 18–21 Cholesterol ester, 233, 234
Cancer research, 285, 286. See also Chromophobe renal cell carcinoma
Raman microscopy for biomedical (ChRCC), 172, 173, 175, 181
applications Citroclear, 69
Cancerous TMA cores, 22–24 Classical least squares (CLS), 184
Carotenoid, 196 Classification accuracy, 10
Carotenoid RRS detection. See Raman Classification protocol optimization,
detection of carotenoids in human 12–14
tissue Classification techniques, 277–278
CARS. See Coherent anti-Stokes CLS, 184
Raman spectroscopy (CARS) Cluster algorithms, 277
CCAM, 239–241 Cluster analysis, 228–229, 277, 293
CCD, 271–272 Coherent anti-Stokes Raman
Cell preparation, 71–92 spectroscopy (CARS), 319–347
Cell stress, 243, 245 advantages, 321
Cells. See Raman imaging of cells atherosclerotic lesions, 340–341
CH-stretch region, 134 basic principles, 324–326
Chapter authors biomedical imaging, 337–341
Bakker Schut, Tom C., 265 breast cancer tissue, 337–339
Bernstein, Paul S., 193 CARS chemical selectivity,
Bhargava, R., 1 328–329
Drauch, Amy, 157 CARS sensitivity, 330–331
Ermakov, Igor V., 193 femtosecond CARS, 321
Evan, Andrew P., 99 first generation CARS microscopes,
Gardner, Peter, 59 322–323
Gazi, Ehsan, 59 FM-CARS, 330–331
Gellermann, Werner, 193 future directions, 342
Giordano, Mario, 29 historical overview, 319–324
Gohr, Claudia, 29 multimodal microscope, 332–333