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Raman spectroscopy. See Raman SERS imaging (Cont.):
imaging PCA, and, 182
Raman spectroscopy of bacteria, SERS scatter, 143
248–259 SPR, 144
imaging single bacteria, 255–259 substrates, 145
species classification, 248–255 TERS, and, 255
ultraviolet wavelength range, 253 variations, 150
visible wavelength range, 249–251 SFTIR imaging. See Synchrotron-based
Raman spectrum, 268 FTIR spectromicroscopy
Ratti, Simona, 29 SFTIR, Raman, and SERS imaging of
Rayleigh criterion, 111 fungal cells, 125–156
Rayleigh scattering, 267 conclusions, 150–151
Receiver operating characteristic fungus, 126, 127–130
(ROC) analysis, 10, 13 introduction, 125–127
Red blood cells, 245–248 Raman spectroscopy of fungi, 137–142
Redman, R. S., 151 sample harvest and preservation, 129
Refractive index, 112–114 SERS imaging. See SERS imaging
Renal oncocytoma (OC), 173 SFTIR spectra of fungi, 133–137
Reprocessed Raman cell maps, 73 spatial resolution, 133
Residual stress patterns, 312–315 specimen preparation, 129–130
Resonance Raman imaging. See Raman spectral resolution, 132
detection of carotenoids in human vibrational spectroscopy, 130–133
tissue Sharifzadeh, Mohsen, 193
Reststrahlen bands, 115 SHG, 332, 333, 336
Reststrahlen effect, 112–113 Sholkina, Mariya, 265
Retina. See Macular pigment (MP) Signal-to-noise ratio (SNR), 112, 163
Rhodamine 6G, 145, 182 SIL, 102
ROC analysis, 10, 13 Silicon, 109
Rodriguez, R. J., 151 Single-cell confocal Raman
Rosenthal, Ann, 29 microscopy, 280
RPMI 1640, 81 Skin carotenoid RRS detection, 215–221
RRS spectroscopy. See Raman detection Smith, Randy, 151
of carotenoids in human tissue Smoothing, 170
SMR, 178–179
S S Snap-freezing, 62, 63
S. epidermidis, 257–258 SNR, 112, 163
Sample preparation. See Preparation of Sodium chloride, 112
tissues and cells Solid immersion lens (SIL), 102
Saprotrophic fungus, 128 Sommer, Andre’ J., 99
Savitsky-Golay smoothing, 170 Sonication, 90
Scanning electron microscopy (SEM), Sorensen, J., 152
133 Spatial resolution, 133
Scatter plot, 172, 174, 176 Spatially resolved resonance Raman
Scattering, 115, 116 imaging of macular pigment,
Schwannoma, 231–233 199–215
SE-CARS, 331 Spectral analysis, 131–132
Second harmonic generation (SHG), Spectral fingerprint region, 14
332, 333, 336 Spectral metrics, 14–15
SEM, 133 Spectral mixture resolution (SMR),
Sequential forward selection process, 178–179
10 Spectral resolution, 132
SERRS, 126, 145, 150 Spectrometer, 271
SERS imaging, 142–150 Split-pea infrared microscope, 103
CARS, and, 331 Spotlight 300 infrared imaging
core of phenomenon, 144 microscope, 107
fungus, 145–150 Spotlight FTIR point mapping, 38
gold nanoparticles, 90 SPR, 144
hot spots, 147 Standard reference material (SRM),
nanodots, 143 166, 167