Page 198 - Materials Chemistry, Second Edition

Determination of Pharmaceutical Compounds in Sewage Sludge 179

References Li et al. (2016)

Limits of Detection (ng g−1 d.w.) 0.117–5.55

Overview of Analytical Methods for the Determination of Pharmaceutical Compounds in Sewage Sludge
Recoveries (%) 50–107

Analytical Determination LC-MS/MS

Clean-up MSPD (C18)

Total Solvent Volume 16 mL ACN: acetonitrile; d-SPE, dispersive solid-phase extraction; EDTA, ethylenediaminetetraacetic acid; GC-MS, gas chromatography–mass spectrometry; GC-MS/MS, gas chromatography–tandem mass spectrometry; GPC, gel permeation chromatography; HPLC-UV-Fl, high performance liquid chromatography with ultravio

Extraction Solvents MeOH (6 mL), ACN:oxalic acid 5% (8:2, v/v) (10 mL) QuEChERS, quick, easy, cheap, effective, rugged and safe; SALLE, salt-assisted liquid-liquid extraction; UAE, ultrasonic-assisted extraction.

Extraction Technique MSPD

Sample Amount 0.1 g
TABLE 9.1 (CONTINUED) Sample Therapeutic Group Sewage 45 pharmaceuti- sludge cals (antibiotics, non-steroidal anti-inflammatory drugs, β-blockers, and antidepressants) a Limits of quantification. b