Page 174 - Basic Gas Chromatography
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Topics  161   GC-MS      GC-MS   of  Capabilities   resolving   high   the  techniques:   both   of  advantages   the  ombines   -   provides   MS   the   while  retained,   is   GC   of  analysis   of   speed   the   and   ower   level.   ppb   the   to   down  analyses  quantitative   and  identification  positive   both   and  systems,   cost   low   for  common   are  Daltons   600   to   10   of  ranges   Mass   $40K   from   range   Costs

   Special                             They   structure   atomic   analytical   as   and   considerable   sector   could   they   generate   a   analyzers   information   requirements   600   The   quadrupole,

          Surface   lons   of   version).   compound.   chemical   separate   an   compounds,   compounds,   products   been   not   early   The   requiring   Magnetic   however,   to   scanning   analytical   huge   much   ““GC-MS”   GC.   MS   the   about   to   high  possessed   “pure”’.   be   (hopefully   rugged   The


         Semi-Conductive   ascade   Detector   (continuous-dynode   each   for   the   and   to  spectrometer   improved   as   unknown   organic   and   petroleum   GC   if   had   Gohlke   [6].   usually   running.   analyzer;   necessary   Faster   was   GC   a   as  provided   the  dedicated   the   for  detector   would   GC,   a   be   limited   be   GC   the   most   cases   devices  scanning   more  simple,   laboratories.   need.







                               multiplier   unique   are   weight   mass   and   identifying   inorganic   of   dramatically   by   1959   in   complex,   and   them   keep   of   type   seconds)   (few   from   GC.   a   that  obvious   detector   born   was   a   as   inlet   could   range   because   in  would   rapid   and  second)   analytical   this   met



                               Electron   present   molecular   a   used   developed   for   of   both   characterization   more   GC   to   cumbersome   to   popular   scanning   eluting   was   GC   no   but   Thus   designed   sample   the   mass   satisfactory   peaks   of   per   routine   in   designs,


                               10.8.     the           slowly   powerful   structures   the   even   coupled   maintenance   most   peak   it   1960s,   MS.   was   that   The   was   eluting   development   times   used   trap
                               Fig.    species   establish   Thompson   was   be   for   grown   first   the   rapid   a   rapidly,   from   MS   simplified.   the   so   be   ion
                                       m/z   to   compound.   J.   MS   to   used   have   was   expensive,   and   were   the   of   required.   late   the   growing   available   new   a   specifying   resolution   the   several   could   the

                                       specific   History   J.   1913,   proved   elucidating   1952.   MS   expertise   provide   spectrum   By   By   be   capabilities   was   Daltons   later,
    160                                  used   each   After   in   widely   would   in   were   ments   be   and   was   where   could   low   part   which   and
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