Page 193 - Chiral Separation Techniques

6.5 Adsorption–Desorption Kinetics and Chromatographic Band Broadening 171

Fig. 6-9. Imprintable brush-type selectors. (From Welch [70].)

can also be imprinted via a sacrificial spacer approach which potentially will result
in a high yield of templated sites exhibiting pronounced selectivity towards the tar-
get peptide (22) [72].
Considering functional group complementarity, other commodity monomers may
also be used. Thus for templates containing acid groups, basic functional monomers
are preferably chosen. The 2- or 4-vinylpyridines (VPY) are particularly well-suited
for the imprinting of carboxylic acid templates and provide selectivities of the same