Page 272 - Chiral Separation Techniques

250 9 Modeling and Simulation in SMB for Chiral Purification

9.7 Conclusions

SMB technology is now a mature technology adopted by pharmaceutical industry.
The existence of an organized body of knowledge [39, 40] was helpful in optimiz-
ing SMB systems and making them acceptable by the industry. The future will
require dynamic simulation for systems with small number of columns, e.g., config-
urations of the type 1-2-2-1 as encountered in some cases and also in view of pro-
cess control to improve process performance.

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