Page 267 - Chiral Separation Techniques
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9.6 Operation of the SMB Unit 245
Fig. 9-16. Competitive adsorption isotherms: experimental (points) and model (lines) results.
Fig. 9-17. Chromatographic response to a feed pulse. Comparison between experimental (points) and
–1
model (lines) results. (Pulse during 7.5 min; flow rate: 5 mL min .)
optimization problem can be simplified if we take into account the functions of the
different sections of a TMB system. Section I, located between the eluent and extract
nodes, must provide the complete regeneration of the adsorbent phase, so the solid
coming out this zone is recycled to section IV completely clean of the two compo-
nents. In other words, both components A and B must move upwards, following the
liquid phase. Because component B is the more retained species, we have to consider
only the constraint considering this component; i.e., if the constraint is fulfilled for
species B, the constraint considering the less retained component A will be always