Page 360 - Color Atlas of Biochemistry

Brain and sensory organs 351

A. Resting potential

Extracellular space
Na Cl
K
Organic
anions
-60 mV
-60 mV

1

A A
Sodium PP P P P Potassium Chloride
channel channel channel
P
Cytoplasm Na Cl
K
Usually Often Organic
closed 1 Na /K ATPase open anions
3.6.1.37

B. Action potential
(mV)
Action potential 2
Membrane potential -20 0 1 Depolarization Ion conductivity Na
+40
2
+20

3
-40
-60
4
-80 Resting potential 1 3 K
Hyperpolarization 4
1 2 3 1 2 3
Time (ms) Time (ms)

Na Na
K K
*

1 1

1 Na 2 Na
K K

Na Na
K K
*

1 1

* Charge reversal
3 Na at membrane 4 Na
K K

Koolman, Color Atlas of Biochemistry, 2nd edition © 2005 Thieme
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