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Exoskeletons in upper limb rehabilitation  247


              fit a shaft along the axis of rotation of above cases (axis of humerus and
              radius), the developer of ETS-MARSE used an antibacklash spur gear
              meshed with open-type semicircular gear and bearing assembly.
                 Harmony (Kim and Deshpande, 2015, 2017) as shown in Fig. 2C, a
              recent robotic exoskeleton in the field of upper limb rehabilitation, has been
              developed intending to enable the patient to do bilateral arm training. This
              system is comprised of a dual arm with four-bar linkage, which makes it
              capable of providing naturalistic shoulder movement. Unlike, ARMin-III
              (where shifting of shoulder CR was considered only for vertical flexion-
              extension), here the four-bar linkage mechanism moved shoulder CR dur-
              ing either shoulder abduction-adduction or vertical flexion-extension,
              which made it more anatomical-like (Kim and Deshpande, 2017). The
              range of motion of the robot differs based on the way its other joints are con-
              figured. For instance, ROM of shoulder abduction increased when it was
              performed simultaneously with shoulder external rotation.


              3 Design requirements and challenges

              Unlike industrial and other genres of robots, upper limb exoskeletons by
              their nature are complex in structure, requiring more sophistication in
              design. Researchers have used different measures and features in upper limb
              exoskeleton design to enhance functionality. However, there are still limi-
              tations that need to be addressed.

              Safety

              Since upper limb exoskeletons have close interactions with wearers, safety is
              paramount. Human-exoskeleton interaction (HEI) must be designed so as to
              ensure safe operation. For safe running of exoskeletons, a HEI should
              include safety measures in mechanical, electronic, and control design.
              Mechanically, safety is ensured by placing physical stoppers in the exoskel-
              eton’s structure to prevent it going beyond natural ROM; safety can also be
              ensured by designing links and exoskeleton robot parts in a way where adja-
              cent links act as physical stoppers in extremes. Electronically, by setting cur-
              rent and voltage limits in motors, exoskeleton joints can be refrained from
              going beyond permissible ROM. In control design, saturation can be set for
              torque, force, velocity, and position to ensure the wearer’s safety during
              exoskeleton failure.
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