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Exoskeletons in upper limb rehabilitation  257


              mechanism should also be novel with light weight, compactness, high gear-
              ratio, friction free, zero backlash, and quick responsiveness. One of the key
              novelties that researchers should include in exoskeleton design is modularity
              (also known as reconfigurability). A modular exoskeleton can be reconfi-
              gured by adding or removing parts/modules to or from it. For instance, a
              7-DOF exoskeleton is redundant for an individual who has disability only
              in the shoulder. In this case, the elbow and wrist motion support parts could
              be removed from it, reducing the 7-DOF exoskeleton to a 3-DOF exoskel-
              eton. Having quick attachable-detachable links in exoskeletons would allow
              it to be modular.
                 Despite the fact that an enormous amount of research has been done,
              development of a control strategy to provide effective rehabilitation is still
              evolving. To provide efficacious rehabilitation to upper limb-impaired
              patients, first, we must determine the patient’s safe extreme ROM before
              starting therapy. This may also help to select appropriate and safe rehabili-
              tation protocols for patients. For example, it is essential to know the safe
              ROM of a patient having muscle tone. In conventional therapy, this is done
              manually by a therapist who observes the patient. Second, the therapist can
              adjust his/her approach if the patient feels any pain or something unwanted
              happens. This is something exoskeletons should include in their control
              design. Third, to the best of the authors’ knowledge, there is no such a con-
              troller that automatically selects a rehabilitation protocol for the patient and
              changes it depending on how the patient is doing exercise. Fourthly, when
              the patient starts sharing control, he/she has to move his/her impaired limb
              as well as exoskeleton before getting assistance. This seems to be a burden
              because the patient has already lost mobility. In such a case, it is worth com-
              pensating a portion of torque required to move the exoskeleton only.




              6 Conclusion
              In this chapter, the HEI, hardware design, safety, compactness, control tech-
              nique, actuation, and power transmission mechanism of existing upper limb
              rehabilitative exoskeletons were reviewed. We found that most research
              prototypes of existing exoskeletons were not transferred into a commercial
              product, and perhaps the reason behind it is the lack of clinical testing.
              Therefore, in this review, the challenges that need to be addressed for
              improved functionality have been identified and discussed. Addressing these
              challenges in the development of exoskeletons will make them more
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