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 Encyclopedia of Physical Science and Technology  EN008M-395  June 29, 2001  15:52







              Magnetic Resonance in Medicine                                                              971

                                                                  In MR spectroscopy, the molecules being studied are
                                                                present in a concentration very low compared to that of
                                                                water. As a consequence, spectroscopy signals tend to
                                                                be very weak. This places an even stronger premium on
                                                                field strength than does imaging. It is widely accepted that
                                                                spectroscopic studies of patients are not warranted in field
                                                                strengths less than about 1.5 T.


                                                                B. Magnets
                                                                The magnet is probably the most significant portion of a
              FIGURE 4 Preparation for scanning. The superconducting mag-
                                                                whole-body scanner. The magnets used vary substantially
              net shown here operates at 1.5 T. (Courtesy of GE Medical
                                                                in terms of field strength, shape, and basic design. How-
              Systems.)
                                                                ever, they all must meet certain basic requirements. One
                                                                obvious requirement is that the magnet be large enough
                                         2
              strength, the signal increases as B . The noise in the sys-  to admit a human body and produce a field strength that
                                         0
              tem can be brought to a very low level by proper design  is intense enough to produce a strong proton NMR signal.
              of the electronics. However, there is some electrical noise  Equally important, though not so obvios, is the require-
              that is generated within the patient and that cannot be re-  ment for high homogeneity, or uniformity of the magnetic
              moved by improved circuit design. The ultimate source of  field strength from one part of the imaging volume to an-
              this noise is the random motion of ions and charged macro-  other. It is essential that, unless gradient coils are being
              molecules within the patient’s body and is of thermal ori-  used to deliberately modulate it, the Larmor precession
              gin. The noise voltage increases approximately linearly  proceed at the same rate throughout the entire portion
              with increasing frequency.                        of the patient that is to be imaged. The homogeneity re-
                A key parameter in determining overall image quality is  quirment puts strong limitations on the acceptable magnet
              the signal-to-noise ratio (SNR). The arguments just given  designs. Superconducting and resistive systems are de-
              indicate that the SNR should increase linearly as the field  signed to provide a cylindrical symmetry. A cylindrical
              strength is increased. This is the basis for the use of strong  opening, called the room temperature bore, is available to
              magnetic fields in NMR scanners. If it is desired to achieve  permit placing the patient into the region of strong and
              high-resolution proton images, thin slices and small pic-  highly homogeneous field.
              ture elements (as will be discussed later) must be used;  At the present time clinical proton imaging is usually
              however, this leads to a decrease in the amount of signal  done using magnetic field strengths in the order of 0.2 to
              available to determine the pixel brightness numbers. If this  1.5 T, although, in about 2000, commercial MRI systems
              process is pushed too far, the images will become grainy  operating at3Tbegan to become available. Later, in the
              because of the effects of the noise. By increasing the field  section on current trends, research scanners operating at
              strength of the magnet, the available signal is increased;  even higher field strengths will be described. The types
              this can be used to support higher resolution imaging.  of magnet that have been used to produce clinical im-
                                                                ages have included permanent magnet systems, iron-core
                                                                electromagnets, and resistive and superconducting mul-
                                                                ticoil magnets. Each of these designs has certain advan-
                                                                tages. However, for producing fields greater than about
                                                                0.5 T, only the superconducting systems are practical;
                                                                field strengths in this range are beyond the capabilities
                                                                of present-day permanent magnet materials. In resistive
                                                                systems the coils are made of a conventional conductor,
                                                                such as copper or aluminum. If enough current is run
                                                                through them to produce whole-body sized fields much
                                                                above 0.2 T, so much heat is generated in the windings
                                                                that even with water cooling there is a likelihood of burn-
                                                                ing the insulation or actually melting the wire.
                                                                  Thephenomenonofsuperconductivityprovidesthebest
              FIGURE 5 NMR scan. The patient has been positioned in the
              center of the magnet and can be seen through a window above  approach to achieving strong magnetic fields. Since 1911
              the operator’s console. (Courtesy of GE Medical Systems.)  it has been known that some materials when cooled to
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